Santamesa is a barangay in Metro Manila, Philippines, located in the city of Manila. It is known for being a densely populated residential area with a mix of old and new housing, as well as commercial establishments. The barangay is situated near major roads and transportation hubs, making it a convenient location for residents and visitors alike. Santamesa is also home to several schools, churches, and community centers, contributing to its vibrant and diverse community. Its strategic location and urban amenities make it a distinctive and desirable place to live in the Manila area.